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Hydrogels for Osteochondral
Tissue Engineering
Journal of Biomedical

(March 2020)
Anti-Wrinkle Activity
& Transdermal Delivery
of GHK Peptide
Journal of Peptide Science
(March 2020)
Pulsed Glow Discharge
to GHK-Cu Determination
International Journal
of Mass Spectrometry

(March 2020)
Protective Effects of GHK-Cu
in Pulmonary Fibrosis
Life Sciences
(January 2020)
Anti-Wrinkle Benefits
of GHK-Cu Stimulating
Skin Basement Membrane
International Journal of Molecular Sciences
(January 2020)
Structural Analysis
Molecular Dynamics of
Skin Protective
TriPeptide GHK
Journal of Molecular Structure
(January 2020)
In Vitro / In Vivo Studies
pH-sensitive GHK-Cu in
Superabsorbent Polymer
GHK Enhances
Stem Cells Osteogenesis
Acta Biomaterialia
Antibacterial GHK-Cu
Nanoparticles for
Wound Healing
Particle & Particle (2019)
Effect of GHK-Cu
on Stem Cells and
Relevant Genes
OBM Geriatrics
GHK Alleviates
Neuronal Apoptosis Due
to Brain Hemorrhage
Frontiers in Neuroscience
Endogenous Antioxidant
International Journal of Pathophysiology and Pharmacology (2018)
Regenerative and
Protective Actions of
GHK-Cu Peptide
International Journal of
Molecular Sciences
Skin Regenerative and
Anti-Cancer Actions
of Copper Peptides
GHK-Cu Accelerates
Scald Wound Healing
Promoting Angiogenesis
Wound Repair and

GHK Peptide Inhibits
Pulmonary Fibrosis
by Suppressing TGF-β1
Frontiers in Pharmacology
Skin Cancer Therapy
with Copper Peptides
The Effect of Human
Peptide GHK Relevant to
Nervous System Function
and Cognitive Decline
Brain Sciences (2017)
Effects of Tripeptide
GHK in Pain-Induced
Aggressive Behavior
Bulletin of Experimental
Biology & Medicine
GHK-Cu Elicits
In Vitro Alterations
in Extracellular Matrix
Am Journal of Respiratory
and Critical Care Medicine

Selected Biomarkers &
Copper Compounds
Scientific Reports

GHK-Cu on Collagen,
Elastin, and Facial Wrinkles
Journal of Aging Science
Tri-Peptide GHK-Cu
and Acute Lung Injury

Effect of GHK Peptide
on Pain Sensitivity
Experimental Pharmacology

New Data of the
Cosmeceutical and
TriPeptide GHK
SOFW Journal
GHK Peptide as a
Natural Modulator of
Multiple Cellular Pathways
in Skin Regeneration
BioMed Research (2015)
Resetting Skin Genome
Back to Health
Naturally with GHK
Textbook of Aging Skin
GHK-Cu May Prevent
Oxidative Stress in Skin
by Regulating Copper and
Modifying Expression of
Numerous Antioxidant Genes Cosmetics (2015)
GHK Increases
TGF-β1 in
Human Fibroblasts

Acta Poloniae

The Human Skin Remodeling Peptide Induces Anti-Cancer
Expression and DNA Repair Analytical Oncology
Resetting the
Human Genome to Health
BioMed Research
Enhanced Tropic Factor Secretion of Mesenchymal
Stem Cells with GHK
Acta Biomater
Anxiolytic (Anti-Anxiety)
Effects of GHK Peptide
Bulletin of Experimental
Biology & Medicine
Lung Destruction and
its Reversal by GHK
Genome Medicine
TriPeptide GHK Induces
Programmed Cell Death
of Neuroblastoma
Journal of Biotechnology
Stem Cell
Recovering Effect
of GHK in Skin
Peptide Science
Skin Penetration of
Copper Tripeptide in Vitro
Journal of International
Inflammation Research
Possible Therapeutics
for Colorectal Cancer
Journal of Clinical and
Experimental Metastasis
Methods of Controlling
Differentiation and
Proliferation of Stem Cells
Effects of
Copper Tripeptide
on Irradiated Fibroblasts
American Medical Association
Avoid Buying Fake Copper Peptides Dangerous

Causes of Dry Skin

During the teen-age years we have excessive skin oil production that leads to acne.

But after age 40, sebum production drops, resulting in a drier skin. Dry skin is also called xerosis, or xerotic eczema (xeros is Greek for "dry").

Xerosis may occur in normal healthy skin or be caused by specific conditions in which the skin fails to secrete adequate oils such as Sjorgen's syndrome.

Generally, as we get older there is a tendency for a drier, less oily skin. When skin becomes too dry, the outer skin layers become stiff and may develop cracks. The cracks become fissures into the skin which become irritated, inflamed and itchy.

Dry skin occurs more during the fall and winter months because of low humidity and too frequent bathing.

Xerosis is often called "Winter Itch" because of its worsening in winter.

The condition is worst in areas of the body with relatively few oil glands such as the arms, legs and torso area.

Some dermatologist feel that xerosis has worsened in recent years because people take more baths and showers. Fifty years ago, most people took one or two baths per week, and the skin had a chance to replace its natural skin oils between baths.

The best cure of dry skin is keeping your skin healthy. However, dermatologists often recommend creams or lotions for the dry cracked skin.

These are products such as Aveeno Lotion, Cetaphil Cream, Curel, Dermasil, Lacticare, Moisturel, Purpose, Neutrogena, or Lubriderm. Use creams for spot treatment and lotions over extensive body areas.

We find that natural alternative oils such as emu oil or squalane work best.




Questions or Advice?

Email Dr. Loren Pickart at

Call us at 1-800-405-1912 Monday Through Friday (8 am to 6 pm) PSTLoren Pickart Skin Biology Facebook

Painting of a Lady with Dry Skin

Cleansers for Sensitive, Dry, and Irritated Skin

Soaps, detergents and bubble baths remove dirt, body oils and bacteria, preventing odor and infection.

Their use can cause itching and irritation. Beauty bar soaps contain synthetic detergents but are generally less drying and irritating.

People with dry skin should choose a very mild soap or soapless cleanser, and use as little soap as possible.

During a episode of very dry skin, bathe/shower with cool water and minimize water contact.

Many soap and cleansers not only remove surface dirt and oils, but actually damage the skin by destroying its natural acid mantle of sebum lipids.

Removal of this protective and anti-oxidant barrier leads to the generation of more skin-damaging free radicals.

This creates a dry, flaky skin which stimulates the production of more oil. The natural acidity of skin ranges from 4.2 to 5.6, but many soaps are very alkaline at around pH 10.

Even mild soaps usually have a very alkaline pH of 9.5. Keep in mind that every change in one pH unit (a logarithmic system) increases alkalinity by 10-fold and a soap of pH 10 has 1,000 times more alkalinity than a soap at pH 7.0.

Fragile skin can literally be dissolved by strong soaps. Becareful of harsh detergents, caustics, or "flash" foaming agents. The pH of the soap is 7.0, far below the alkalinity of other soaps.

Dr. Peter Pugliese, more of the world's most innovative dermatologists, Pugliese designed a cleanser built around a ultra-light oil derived from soybean oil. This cleansing oil is formulated to dissolve makeup and dirt while leaving the skin's natural lipid barrier intact.

monet with water lily